To compare the efficacy of depot leuprolide and oral progesterone in management of heavy menstrual bleeding due to fibroid
Not Applicable
- Conditions
- Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified
- Registration Number
- CTRI/2021/10/037049
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
PRESENTING TO GYNAE OPD OF LHMC AND SSKH WITH CYCLICAL HEAVY MENSTRUAL BLEEDING AND DIAGNOSED WITH LEIOMYOMA ON USG
Exclusion Criteria
1 KNOWN CASE OF UNCONTROLLED HYPOTHYROIDISM
2 WOMEN WITH ANTICOAGULANTS
3 WOMEN WITH HEMOGLOBIN LESS THAN 5 GM PER DL WITH HEMODYNAMIC INSTABILITY
4 UNCONTROLLED DIABETES
5 UNCONTROLLED HYPERTENSION
6 MIGRAINE
7 HISTORY OF THROMBOEMBOLIC EPISODES
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Proportion of women with PBAC score of 50 or less in depot leuprolide and oral norethisterone group after first and second cycle <br/ ><br>Timepoint: First and second of treatment
- Secondary Outcome Measures
Name Time Method 1.Proportion of women with improvement in hemoglobin level of 1 gm% at 1 month and 2gm% at 2 month in group A& B <br/ ><br>2.Proportion of women with improvement in myoma volume of 15% at 1 month and 25% at 2 month group A & B <br/ ><br> <br/ ><br>Timepoint: First and second cycle of treatment <br/ ><br>