Monitoring the effects of Antihypertensives(ACE Inhibitors / ARBS)in patients undergoing surgey
Not Applicable
Completed
- Conditions
- Health Condition 1: I10-I16- Hypertensive diseases
- Registration Number
- CTRI/2020/06/025892
- Lead Sponsor
- Kasturba Medical College Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
All adult hypertensive patients, of either gender on treatment with angiotensin converting enzyme inhibitors or Angiotensin receptor blockers who are scheduled for elective surgery will be enrolled in the study.
Exclusion Criteria
PREGNANT WOMEN
AGE <18YEARS
TERMINALLY ILL
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of deviation of mean blood pressure 30% from the baseline (as recorded during preoperative visit) intraoperatively <br/ ><br>Timepoint: Baseline (preop) <br/ ><br>Immediate preop <br/ ><br>After induction <br/ ><br>After intubation 1 min <br/ ><br>2 min <br/ ><br>3 min <br/ ><br>5 min <br/ ><br>10 min <br/ ><br>15 min <br/ ><br>30 min <br/ ><br>1 hr <br/ ><br>2 hr <br/ ><br>Hourly till extubation <br/ ><br>Before extubation <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)Incidence of deviation of mean blood pressure 30% from the baseline (as recorded during preoperative visit) postoperatively <br/ ><br>2)Need for treatment of deviation in blood pressure (with vasoconstrictors/vasodilators) intraoperatively and postoperatively <br/ ><br>3)Any other adverse event attributable to ACE inhibitor/ARB continuation/discontinuation. <br/ ><br>Timepoint: After extubation <br/ ><br>1 min <br/ ><br>5 min <br/ ><br>30 min <br/ ><br>1 hr <br/ ><br>6 hr <br/ ><br>12 hr <br/ ><br>18 hr <br/ ><br>24 hr <br/ ><br>