CTRI/2018/05/013588
Completed
N/A
A comparitive study of efficacy of preoperative administration of single high dose intravenous tranexamic acid versus multiple boluses of intravenous tranexamic acid in primary total knee arthroplasty - TAKR
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Total blood loss in total knee replacement.
- Sponsor
- SUNSHINE HOSPITALS
- Enrollment
- 300
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Informed consent
- •Those undergoing primary unilateral knee replacement.
Exclusion Criteria
- •Abnormal PT/APTT/INR or coagulopathic diseases
- •Undergoing B/L TKR / revision surgeries of any cause
- •Past h/o thromboembolic events
- •Treated with Aspirin or any anti\-platelets within 1 week prior to the surgery
- •TKR done for secondary OA (rheumatoid arthritis, post traumatic arthritis)
- •History of reported allergy to tranexamic acid
- •Pre operative hemoglobin \<8gm/dl
- •Chronic renal insufficiency
Outcomes
Primary Outcomes
Not specified
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