Respiratory signal driven breathing instructions to improve spatial alignment between respiratory gated PET and breath-hold CT
Completed
- Conditions
- lung cancerpulmonary carcinoma10038666
- Registration Number
- NL-OMON42538
- Lead Sponsor
- Radiologie en Nucleaire Geneeskunde
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
Patients with suspected lung malignancy, who will have a PET/CT scan.
Exclusion Criteria
Mentally incompetent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The mismatch between PET and CT measured for standard low-dose CT and PET, and<br /><br>breath-hold low-dose CT and PET for 1 anatomical location (lung-liver<br /><br>transition)</p><br>
- Secondary Outcome Measures
Name Time Method <p>The mismatch between PET and CT measured for standard low-dose CT and PET and,<br /><br>breath hold low-dose CT and PET for lung lesions, measured by:<br /><br>• Mismatch between centroids of the lesions on PET and CT<br /><br>• Mismatch between lesions on PET and CT measured with the Jaccard similarity<br /><br>coefficient<br /><br>• Effect of attenuation correction of the CT on the PET reconstruction measured<br /><br>by the mean tracer uptake.</p><br>