Examining the response to chemo-radiotherapy treatment of Glioma tumor using MRI method versus Experimental method

Not Applicable

Recruiting

• Conditions: Glioma cancer.; Disorder of central nervous system, unspecified; G96.9

• Registration Number: IRCT20230904059352N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Patients suffering from types of glioma

Exclusion Criteria

Tumor recurrence and history of RT-CRT treatment
Central Nervous System (CNS) disorders such as epilepsy and stroke
Patients with missing data
Patients whose total resection of the Tumor was not possible and left the follow-up study due to Disease recurrence and the need for special treatment.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy of predicting response to chemo-radiotherapy (to detect improvement, progression, pseudo-progression). Timepoint: One-six month after treatment. Method of measurement: Magnetic Response imaging - Response Assessment in Neuro-Oncology (RANO) Criteria.

Secondary Outcome Measures

Name	Time	Method
Therapeutic volumes based on RANO criteria. Timepoint: One and six months after chemo-radiotherapy. Method of measurement: The values of quantitative MRI indicators and treatment volumes can be calculated automatically by the software. The RANO Criteria is a decision-making rule in relation to the volumes and response to treatment.