Skip to main content
MedPathMedPath Home
Clinical Trials/NCT02180191
NCT02180191
Completed
Not Applicable

Comparison of Gut Microbiota in Obese, Diabetic and Healthy Control Individuals

Gulhane School of Medicine1 site in 1 country81 target enrollmentJanuary 2013
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsObesityType 2 Diabetes Mellitus

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
Gulhane School of Medicine
Enrollment
81
Locations
1
Primary Endpoint
The comparison of the gut microbiota composition
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

An altered gut microbiota composition has recently been linked to obesity and diabetes. The principal aim of this study was to investigate and compare the gut microbiota composition of obese, diabetic and control individuals. Then, associations between analyzed gut microbial concentrations and clinical-biochemical blood parameters were assessed.

Registry
clinicaltrials.gov
Start Date
January 2013
End Date
September 2013
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Gulhane School of Medicine
Responsible Party
Principal Investigator
Principal Investigator

Yalcin Basaran

MD

Gulhane School of Medicine

Eligibility Criteria

Inclusion Criteria

  • •Subjects with obesity or newly diagnosed type 2 diabetes
  • •18 years to 65 years of age

Exclusion Criteria

  • •Any chronic disease (other than obesity and diabetes)
  • •Alcohol consumption/smoking
  • •Pregnancy/breastfeeding
  • •The use of antibiotics, pro-prebiotics within 3 months
  • •\<18 years or \>65 years
  • •History of intestinal surgery

Outcomes

Primary Outcomes

The comparison of the gut microbiota composition

Time Frame: 9 months

The gut microbiota composition of obese, diabetic and control individuals was analyzed by quantitative real-time PCR (qRT-PCR)

Secondary Outcomes

  • The relationship between metabolic parameters and the gut microbiota composition(9 months)

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Intestinal Microbiota in Patients Before and After Bariatric Surgery and Healthy ControlsObesity
NCT02563119University Hospital, Basel, Switzerland70
Unknown
Phase 4
Evaluate the Effect of Saxagliptin on Gut Microbiota in Patients With Newly Diagnosed Type 2 DiabetesType 2 DiabetesObesity
NCT02583438Beijing Chao Yang Hospital100
Recruiting
Not Applicable
Dissecting Host-microbiome Modifiers of Type 2 Diabetes RiskType 2 Diabetes
NCT04579900Laval University40
Completed
Not Applicable
Gut Microbiota Changes in Obese Individuals Undergoing Dedicated Lifestyle Modification ProgramsObesity
NCT02855242Mayo Clinic32
Completed
Not Applicable
The analysis of gut flora in diabetes and metabolic syndromediabetes and metabolic syndrome
JPRN-UMIN000010946Keio University School of Medicine100