NCT02180191已完成不适用
Comparison of Gut Microbiota in Obese, Diabetic and Healthy Control Individuals
Gulhane School of Medicine1 个研究点 分布在 1 个国家目标入组 81 人开始时间: 2013年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- The comparison of the gut microbiota composition
研究概览
简要总结
An altered gut microbiota composition has recently been linked to obesity and diabetes. The principal aim of this study was to investigate and compare the gut microbiota composition of obese, diabetic and control individuals. Then, associations between analyzed gut microbial concentrations and clinical-biochemical blood parameters were assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects with obesity or newly diagnosed type 2 diabetes
- •18 years to 65 years of age
排除标准
- •Any chronic disease (other than obesity and diabetes)
- •Alcohol consumption/smoking
- •Pregnancy/breastfeeding
- •The use of antibiotics, pro-prebiotics within 3 months
- •<18 years or >65 years
- •History of intestinal surgery
结局指标
主要结局
The comparison of the gut microbiota composition
时间窗: 9 months
The gut microbiota composition of obese, diabetic and control individuals was analyzed by quantitative real-time PCR (qRT-PCR)
次要结局
- The relationship between metabolic parameters and the gut microbiota composition(9 months)
研究者
Yalcin Basaran
MD
Gulhane School of Medicine
研究点 (1)
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