Effcacy of lacosomide on refractory focal seizures
- Conditions
- seizure.ICD-10-CM
- Registration Number
- IRCT20211104052968N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
All children from 6 months to 16 years of age with focal seizures who have been diagnosed with at least one previous electroencephalogram and do not respond well to routine treatments despite appropriate treatment with at least two anticonvulsants within 8 weeks of enrollment. They have had at least two relapses in four weeks and have not been in complete control for three weeks, and have not changed their doses of other anticonvulsant drugs in the two weeks prior to enrollment.
Previous administration of lacosamide as an anticonvulsant for at least two months prior to the examination
renal deaseies
Inability to tolerate the drug due to side effects
Seizures caused by a progressive brain or neurodegenerative disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reducing the severity and severity of seizures in children 6 months to 16 years according to the definition of refractory seizures in Nelson's book. Timepoint: Patients' seizures were monitored after the drug reached the therapeutic dose, which is six weeks, and then three months later. Method of measurement: The severity of seizures as a percentage and includes 8 categories 0 - 25, 25-50, 50 to 75 and 75 to 100% in the range of negative to positive 100% based on the initial rate of seizures.
- Secondary Outcome Measures
Name Time Method