Early Diabetes Resolution After Weight Loss Surgery
Completed
- Conditions
- ObesityDiabetes
- Interventions
- Procedure: Weight loss surgeryProcedure: Laparoscopic abdominal surgeries
- Registration Number
- NCT00790309
- Lead Sponsor
- Vanderbilt University Medical Center
- Brief Summary
The primary objective is to compare inflammatory, hormonal, and metabolic changes in the very short term after various bariatric surgical procedures (Roux-en Y Gastric Bypass, Vertical Sleeve Gastrectomy, and Adjustable Gastric Banding)and other abdominal surgeries, as well as to compare these changes to diet-induced changes in the same population.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Not provided
Exclusion Criteria
- Development of an intercurrent infection
- Prior gastric, duodenal, proximal jejunal surgery or pancreas resection
- Current use of thiazolidinediones
- Current use of dipeptidyl peptidase-IV inhibitors (e.g., sitagliptin) or glucagon-like peptide-1 analogs (e.g., exenatide)
- Any condition felt by the PI or co-investigators to interfere with ability to complete the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Weight loss surgery Weight loss surgery This group will be comprised of people having weight loss surgery: Roux-en Y gastric bypass, vertical sleeve gastrectomy, or adjustable gastric banding Abdominal surgery Laparoscopic abdominal surgeries This group will be comprised of people having abdominal surgeries such as nissen fundoplication or cholecystectomy.
- Primary Outcome Measures
Name Time Method Determine to what extent improvements in glycemic control can be attributed to caloric restriction after weight loss surgery 10 days post-op
- Secondary Outcome Measures
Name Time Method Determine changes in inflammatory markers after weight loss surgery 10 days post-op