临床试验/NCT00790309

NCT00790309已完成不适用

Hormonal and Inflammatory Parameters Affecting Early Diabetes Resolution Following Weight Loss Surgery

Vanderbilt University Medical Center0 个研究点目标入组 75 人开始时间: 2008年12月最近更新: 2017年4月21日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Vanderbilt University Medical Center
入组人数: 75
主要终点: Determine to what extent improvements in glycemic control can be attributed to caloric restriction after weight loss surgery

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The primary objective is to compare inflammatory, hormonal, and metabolic changes in the very short term after various bariatric surgical procedures (Roux-en Y Gastric Bypass, Vertical Sleeve Gastrectomy, and Adjustable Gastric Banding)and other abdominal surgeries, as well as to compare these changes to diet-induced changes in the same population.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 65 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

未提供

排除标准

•Development of an intercurrent infection
•Prior gastric, duodenal, proximal jejunal surgery or pancreas resection
•Current use of thiazolidinediones
•Current use of dipeptidyl peptidase-IV inhibitors (e.g., sitagliptin) or glucagon-like peptide-1 analogs (e.g., exenatide)
•Any condition felt by the PI or co-investigators to interfere with ability to complete the study

结局指标

主要结局

Determine to what extent improvements in glycemic control can be attributed to caloric restriction after weight loss surgery

时间窗: 10 days post-op

次要结局

Determine changes in inflammatory markers after weight loss surgery(10 days post-op)

研究者

发起方

Vanderbilt University Medical Center

申办方类型

Other

责任方

Principal Investigator

主要研究者

Naji Abumrad

Chairman, Department of Surgery

Vanderbilt University Medical Center

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