Effect of Dark chocolate consumption in hypertensive type 2 diabetes
- Conditions
- Type 2 Diabetes.Diabetes mellitus
- Registration Number
- IRCT138812222602N3
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Being volunteer or wishing to attend, 35-65 y old, diagnosed with type 2 diabetes for at least 1 year (FPG = 126 mg/dl or 2hPG = 200 mg/dl), BMI = 40 kg/m2, HbA1C < 9%, Blood pressure = 130/80 mmHg and no regular use of any drugs or supplements with antioxidative (ß-carotene, vitamins C or E) or lipid-lowering properties. Exclusion criteria: Allergy to chocolate, Taking insulin, Smoking cigarette, drinking alcohol or drug abuse, congestive heart failure, malignancies, chronic kidney , hepatic and thyroid diseases , severe cardiac arrhythmias, inflammation following vegetarian or weight-reducing diet 2 months before the study ,Changing medication dosage or physical activity level 2 mo before or during the study.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decrease Low Density Lipoprotein. Timepoint: 8 weeks. Method of measurement: Laboratory kit.;Decrease blood pressure. Timepoint: 8 week. Method of measurement: sphygmomanometer.;Decrease Apo B. Timepoint: 8 weeks. Method of measurement: immunoturbidimetry.;Increase ApoA-1. Timepoint: 8 weeks. Method of measurement: immunoturbidimetry.;Decrease Triglyceride (TG). Timepoint: 8 weeks. Method of measurement: Laboratory Kit.;Decrease Fasting Blood Sugar (FBS). Timepoint: 8 weeks. Method of measurement: Enzymatic.;Decrease high sensitivity C-reactive protein (hs-CRP). Timepoint: 8 weeks. Method of measurement: Immunoturbidimetry.;Decrease HbA1C. Timepoint: 8 weeks. Method of measurement: Laboratory Kit.
- Secondary Outcome Measures
Name Time Method