NCT00232674已完成4 期
The Effect of Inhaled Corticosteroids on the Development of Emphysema in Smokers Assessed by Computed Tomography (CT).
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 240
- 试验地点
- 2
- 主要终点
- The primary variable in the study was change in lung density measured by Computed Tomography annually.
研究概览
简要总结
To assess the effect of up to 4 years treatment with budesonide on progression of emphysema in patients with Chronic Obstructive Lung Disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical Chronic Obstructive Pulmonary Disease diagnosis
排除标准
- •No exacerbation within the last 30 days
- •no long term use of oral corticosteroids
结局指标
主要结局
The primary variable in the study was change in lung density measured by Computed Tomography annually.
次要结局
- Decline in lung Function (FEV1) and exacerbation rate were measured biannually and decline in diffusion capacity (TLCO) annually.
研究者
研究点 (2)
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