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Clinical Trials/NCT03870789
NCT03870789
Unknown
N/A

Field Paramedic Application of Sepsis Triage

Hamilton Health Sciences Corporation1 site in 1 country400 target enrollmentDecember 11, 2016
ConditionsSepsis

Overview

Phase
N/A
Intervention
Not specified
Conditions
Sepsis
Sponsor
Hamilton Health Sciences Corporation
Enrollment
400
Locations
1
Primary Endpoint
Accuracy of HEWS
Last Updated
7 years ago

Overview

Brief Summary

Given the implementation of the Hamilton Early Warning Score (HEWS) and the use of capnography by paramedics, this study will involve a large multi-site retrospective evaluation (before vs after implementation) of the HEWS score and comparison of the HEWS to systemic inflammatory response syndrome (SIRS), quick Sepsis Related Organ failure Assessment (qSOFA) and Modified Early Warning Score (MEWS) when applied retrospectively for the identification of sepsis in the prehospital setting.

Detailed Description

1. To determine the accuracy of the HEWS score, compared to qSOFA, and SIRS for early sepsis recognition when used in the prehospital setting by paramedics for the identification of patients with sepsis or suspected sepsis. 2. To evaluate the addition of ETCO2 values to predict mortality in patients who screen positive for sepsis. 3. To identify the before and after healthcare outcomes of a prehospital sepsis alert program.

Registry
clinicaltrials.gov
Start Date
December 11, 2016
End Date
December 31, 2019
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Any patient to which paramedics apply the Hamilton Early Warning Score or patients who arrive to the Emergency Department (ED) by ambulance without a pre-alert and meet the definition of sepsis in the ED will also be included, and patient is ≥ 18 years

Exclusion Criteria

  • Patient is an inter-facility transfer, or patients with absent vital signs are absent, or death before blood can be drawn in the Emergency Department, or the patient fits the criteria for another prehospital alert (ST-elevation myocardial infarction, cerebrovascular vascular accident, or trauma)

Outcomes

Primary Outcomes

Accuracy of HEWS

Time Frame: 1 year

To determine the accuracy of the HEWS score, compared to qSOFA, and SIRS for early sepsis recognition when used in the prehospital setting by paramedics for the identification of patients with sepsis or suspected sepsis.

Secondary Outcomes

  • Evaluate the addtion of end-tidal carbon dioxide (ETCO2) values(1 year)
  • Evaluate sepsis alert program(2 years)

Study Sites (1)

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