ISRCTN52731862进行中（未招募）2 期
Seizure control via pH manipulation: a phase II double blind RCT of inhaled carbogen as adjunctive treatment of paediatric convulsive status epilepticus.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 入组人数
- 424
研究概览
简要总结
2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/38812049/ (added 30/05/2024)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Presenting to Paediatric Emergency Department (ED) of a participating site
- •2. Exhibiting signs of Convulsive Status Epilepticus (CSE) (i.e. ongoing generalised tonic-clonic, generalised clonic or focal clonic convulsive seizure activity) requiring – in the view of the treating physician - emergency treatment either according to standard APLS guidelines or the child’s personalised rescue care plan in order to try and terminate the presenting seizure
排除标准
- •1. Known to have been previously enrolled in CRESCENT
- •2. Infantile spasms (West Syndrome)
- •3. Non-epileptic seizure (pseudo status epilepticus”)
- •4. Tonic posturing due to suspected brain herniation
- •5. Has received phenytoin, levetiracetam, phenobarbital or valproate as part of the management of this episode of status epilepticus
研究者
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