Comparison of the effect of topical and oral isotretinoin in treatment of frontal fibrosing alopecia

Phase 3

Recruiting

• Conditions: Frontal fibrosing alopecia.; Other cicatricial alopecia; L66.8

• Registration Number: IRCT20200314046767N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 April 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

Patients with facial papules diagnosed on the basis of clinicopathological evidence. (Evidence of inflammation and fibrosis seen in papules).

Exclusion Criteria

Pregnant or intended to be pregnant patients
Lactating patients
Patients with a history of allergy to retinoid compounds
Known liver or kidney disease or abnormalities in related blood tests (leukopenia, moderate to severe hypercholesterolemia, hypertriglyceridemia, hypothyroidism, liver and kidney dysfunction)
Patients with a history of pseudotumor cerebri
Patients with a history of suicidal ideation
Patients taking drugs that interact with isotretinoin

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recovery score based on Global Aesthetic Improvement Scale. Timepoint: Before the start of the study and 1 , 2 , 3 months after the start of treatment. Method of measurement: Grading the scale of global aesthetics based on observation.