Effect of isotretinoin on the results of rhinoplasty

Phase 3

Recruiting

• Conditions: rhinoplasty.; Acquired deformity of nose; M95.0

• Registration Number: IRCT20240204060896N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients with thick nasal skin
Patients undergo rhinoplasty for the first time

Exclusion Criteria

Allergy to vitamin A
Pregnancy or intention to become pregnant within the next year and breastfeeding (isotretinoin is contraindicated)
Simultaneously suffering from liver, kidney and heart diseases (isotretinoin is contraindicated)
Hyperlipidemia (isotretinoin is contraindicated)
History of rhinoplasty
Skin diseases that change the thickness of the nose, such as rhinophyma

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scars. Timepoint: 1month, 3 months and 6 months after surgery. Method of measurement: The method of variable measurement is qualitative, in the following way, in the follow-up visit after surgery, post-operative photos are taken and compared with preoperative photos by a plastic and reconstructive surgeon.;Deformation of nasal cartilage. Timepoint: 1month, 3 months and 6 months after surgery. Method of measurement: The method of variable measurement is qualitative, in the following way, in the follow-up visit after surgery, post-operative photos are taken and compared with preoperative photos by a plastic and reconstructive surgeon.