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Effect of Roxadustat on Cardiometabolism

Phase 1
Conditions
Risk factors of cardiovascular disease, metabolic syndrome
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]
Registration Number
CTIS2023-508183-29-00
Lead Sponsor
Pohjois-Pohjanmaan hyvinvointialue
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
24
Inclusion Criteria

Body mass index over 20 kg/m2 and body weight below 100 kg, Good general health based upon the results of the medical history, laboratory tests, physical examination, and 12-lead ECG as assessed by the investigator

Exclusion Criteria

Regular medication (not including hormonal intrauterine device), Fear of pricking and previous difficult blood sampling, Significant diseases, Systolic blood pressure over 150 mmHg, Hemoglobin levels above Finnish reference values, Pregnancy or breast feeding, WOCBP not using very potent contraception during study periods and one week after, Previous venous thrombosis or previous convulsions, Family history of significant venous thrombosis, Familial galactose intolerance, total lactase deficiency or absorbtion deficiency of glucose and galactose, Allergy to peanut or soy, Unable to speak Finnish, Significant surgery 6 months before trial, Participation in another clinical trial one month before beginning of the trial, Abuse of alcohol or medicines or use of drugs

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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