Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes

Completed

• Conditions: Mood Disorders
• Interventions: Procedure: IVF procedure

• Registration Number: NCT01032421
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment. The secondary goal of this study is to explore psychological profiles and coping mechanisms of women undergoing IVF, and to identify the ones that are associated with successful psychological adaptation to the process and a successful biological outcome.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-01
• Primary Completion: 2007-12
• Study Completion: 2007-12
• Study First Submitted: 2009-11-25
• Status Verified: 2009-12
• Study First Submitted QC: 2009-12-13
• Last Update Submitted: 2009-12-13
• Study First Posted: 2009-12-15
• Last Update Posted: 2009-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. Admitted for their first or second IVF cycle;
2. Demonstrated sufficient communication skills and level of understanding in the Hebrew language;
3. signed an informed consent;
4. Were under the age of 42;
5. Were not suffering from endometriosis or male factor in patients who underwent testicular sperm extraction (TESE);
6. Were not under psychotherapeutic or psychopharmacological treatment. The accepted indications for the IVF included a female factor, male factor or unexplained infertility.

Exclusion Criteria

1. All others.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
GNRH	IVF procedure	Observational (IVF is not done as part of the study)