NCT04697160已完成不适用
An Observational Retrospective Cohort Study of Systemic Therapies for Relapsed or Refractory Diffuse Large B Cell Lymphoma (R/R DLBCL), to Compare Outcomes to Those From Tafasitamab + Lenalidomide in the L-MIND Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- MorphoSys AG
- 入组人数
- 3,573
- 试验地点
- 1
- 主要终点
- Overall Survival (OS)
研究概览
简要总结
To compare the efficacy outcomes of the L-MIND cohort with the effectiveness in a matched patient population treated with systemic NCCN/ESMO guideline listed regimens administered in routine clinical care.
详细描述
This retrospective observational cohort study aims to generate a historical control consisting of R/R DLBCL patients who received currently guideline recommended therapies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Overall Survival (OS)
时间窗: through study completion, an average of 1 year
次要结局
- Overall/Objective Response Rate (ORR)(through study completion, an average of 1 year)
- Complete Response Rate (CR)(through study completion, an average of 1 year)
- Duration of Response (DoR)(through study completion, an average of 1 year)
- Event Free Survival (EFS)(through study completion, an average of 1 year)
- Time to next treatment (TTNT)(through study completion, an average of 1 year)
- Progression Free Survival (PFS)(through study completion, an average of 1 year)
- Treatment discontinuation rate due to adverse events(through study completion, an average of 1 year)
- Duration of treatment exposure(through study completion, an average of 1 year)
研究者
研究点 (1)
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