MedPath

MorphoSys

MorphoSys logo
🇩🇪Germany
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
524
Market Cap
$2.8B
Website
http://www.morphosys.de
Introduction

MorphoSys AG is a biopharmaceutical company dedicated to the discovery, development and commercialization of therapies for people living with cancer and autoimmune diseases. MorphoSys is advancing its own pipeline of new drug candidates and has created antibodies that are developed by partners in different areas of unmet medical need. Tremfya (guselkumab) - developed by Janssen Research & Development, LLC and marketed by Janssen Biotech, Inc. for the treatment of plaque psoriasis - became the first drug based on MorphoSys antibody technology to receive regulatory approval. The U.S. Food and Drug Administration granted accelerated approval of the company's proprietary product Monjuvi (tafasitamab-cxix) in combination with lenalidomide for patients with a certain type of lymphoma.

Clinical Trials

71

Active:56
Completed:11

Trial Phases

2 Phases

Phase 1:53
Phase 2:6

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (59 trials with phase data)• Click on a phase to view related trials

Phase 1
53 (89.8%)
Phase 2
6 (10.2%)

Observational Retrospective Cohort Study of Systemic Therapies for R/R DLBCL

Completed
Conditions
Diffuse Large B Cell Lymphoma
First Posted Date
2021-01-06
Last Posted Date
2021-10-20
Lead Sponsor
MorphoSys AG
Target Recruit Count
3573
Registration Number
NCT04697160
Locations
🇬🇧

MorphoSys Research Site, Westcliff-on-Sea, United Kingdom

Expanded Access Program for Tafasitamab (MOR00208) in R/R DLBCL

Conditions
DLBCL
First Posted Date
2020-03-09
Last Posted Date
2020-08-28
Lead Sponsor
MorphoSys AG
Registration Number
NCT04300803

Lenalidomide Monotherapy in R/R DLBCL

Completed
Conditions
Diffuse Large B Cell Lymphoma
First Posted Date
2019-11-04
Last Posted Date
2022-08-24
Lead Sponsor
MorphoSys AG
Target Recruit Count
490
Registration Number
NCT04150328
Locations
🇪🇸

MorphoSys Research Site, Salamanca, Spain

🇮🇹

MorphoSys Research State, Novara, Italy

Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL

Phase 1
Completed
Conditions
Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2019-10-22
Last Posted Date
2024-10-16
Lead Sponsor
MorphoSys AG
Target Recruit Count
66
Registration Number
NCT04134936
Locations
🇪🇸

MorphoSys Research Site, Vitoria-Gasteiz 1009, Spain

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

Phase 2
Completed
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
Biological: Tafasitamab
First Posted Date
2015-12-28
Last Posted Date
2021-12-20
Lead Sponsor
MorphoSys AG
Target Recruit Count
24
Registration Number
NCT02639910
Locations
🇬🇧

Clinical Study Site, Leeds, United Kingdom

  • Prev
  • 1
  • 2
  • 3
  • Next

News

Molecular Partners Appoints Martin Steegmaier as Chief Scientific Officer to Advance DARPin Therapeutics Pipeline

Molecular Partners has appointed Martin Steegmaier, Ph.D. as Chief Scientific Officer effective October 1, 2025, bringing extensive oncology drug development experience from senior roles at Roche, MorphoSys, Boehringer Ingelberg, and SOTIO Biotech.

Vor Bio Secures Global Rights to Telitacicept in $4+ Billion Deal with RemeGen

Vor Bio acquired exclusive global rights (excluding Greater China) to develop and commercialize telitacicept, a dual-target fusion protein approved in China for multiple autoimmune diseases including generalized myasthenia gravis.

Maxion Therapeutics Strengthens Leadership with Appointment of Dr. Stefan Härtle as Chief Development Officer

Maxion Therapeutics has appointed Dr. Stefan Härtle as Chief Development Officer, bringing nearly 20 years of pharmaceutical R&D experience to advance the company's KnotBody® platform into clinical trials.

Essential Thrombocythemia Market Set for Significant Growth as Novel Therapies Enter Pipeline

Essential thrombocythemia affects approximately 167,000 individuals in the US as of 2024, with 75% of cases linked to JAK2 gene mutations and only one approved therapy currently available in Europe.

TREMFYA Becomes First IL-23 Inhibitor to Reduce Structural Damage in Psoriatic Arthritis

Johnson & Johnson's TREMFYA (guselkumab) achieved both primary and secondary endpoints in Phase 3b APEX study, demonstrating significant reduction in symptoms and structural damage progression in active psoriatic arthritis at 24 weeks.

Knight Therapeutics Launches Minjuvi for Relapsed/Refractory DLBCL in Mexico

Knight Therapeutics has launched Minjuvi (tafasitamab) in Mexico for adult patients with relapsed or refractory diffuse large B-cell lymphoma who are ineligible for autologous stem cell transplantation.

Biogen Initiates Phase 3 TRANSCEND Trial of Felzartamab for Late Antibody-Mediated Kidney Transplant Rejection

Biogen has begun dosing in the Phase 3 TRANSCEND study evaluating felzartamab against placebo in approximately 120 adult kidney transplant recipients with late antibody-mediated rejection (AMR).

Biopharma M&A Activity Reaches $79.4 Billion in 2024 Despite 50% Drop from Previous Year

Biopharma M&A activity totaled $79.4 billion in 2024, representing approximately half of 2023's total value, though deal volume saw a slight increase when excluding four mega-deals from the previous year.

FDA Clears Novel Electronic Patch for Premature Ejaculation Treatment

Morari Medical's innovative MOR device, a drug-free patch using electrical stimulation to delay ejaculation, has received FDA clearance for improving sexual performance in adult males.

Novartis to Close MorphoSys Sites, Cut 330 Jobs Amid Pelabresib Development Challenges

Novartis announces closure of MorphoSys facilities in the US and Germany, affecting 330 jobs, following its $2.9 billion acquisition of the German biotech company.

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.