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MorphoSys

MorphoSys logo
🇩🇪Germany
Ownership
Public, Subsidiary
Established
1992-01-01
Employees
524
Market Cap
$2.8B
Website
http://www.morphosys.de
Introduction

MorphoSys AG is a biopharmaceutical company dedicated to the discovery, development and commercialization of therapies for people living with cancer and autoimmune diseases. MorphoSys is advancing its own pipeline of new drug candidates and has created antibodies that are developed by partners in different areas of unmet medical need. Tremfya (guselkumab) - developed by Janssen Research & Development, LLC and marketed by Janssen Biotech, Inc. for the treatment of plaque psoriasis - became the first drug based on MorphoSys antibody technology to receive regulatory approval. The U.S. Food and Drug Administration granted accelerated approval of the company's proprietary product Monjuvi (tafasitamab-cxix) in combination with lenalidomide for patients with a certain type of lymphoma.

Observational Retrospective Cohort Study of Systemic Therapies for R/R DLBCL

Completed
Conditions
Diffuse Large B Cell Lymphoma
First Posted Date
2021-01-06
Last Posted Date
2021-10-20
Lead Sponsor
MorphoSys AG
Target Recruit Count
3573
Registration Number
NCT04697160
Locations
🇬🇧

MorphoSys Research Site, Westcliff-on-Sea, United Kingdom

Expanded Access Program for Tafasitamab (MOR00208) in R/R DLBCL

Conditions
DLBCL
First Posted Date
2020-03-09
Last Posted Date
2020-08-28
Lead Sponsor
MorphoSys AG
Registration Number
NCT04300803

Lenalidomide Monotherapy in R/R DLBCL

Completed
Conditions
Diffuse Large B Cell Lymphoma
First Posted Date
2019-11-04
Last Posted Date
2022-08-24
Lead Sponsor
MorphoSys AG
Target Recruit Count
490
Registration Number
NCT04150328
Locations
🇪🇸

MorphoSys Research Site, Salamanca, Spain

🇮🇹

MorphoSys Research State, Novara, Italy

Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL

Phase 1
Completed
Conditions
Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2019-10-22
Last Posted Date
2024-10-16
Lead Sponsor
MorphoSys AG
Target Recruit Count
66
Registration Number
NCT04134936
Locations
🇪🇸

MorphoSys Research Site, Vitoria-Gasteiz 1009, Spain

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

Phase 2
Completed
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
Biological: Tafasitamab
First Posted Date
2015-12-28
Last Posted Date
2021-12-20
Lead Sponsor
MorphoSys AG
Target Recruit Count
24
Registration Number
NCT02639910
Locations
🇬🇧

Clinical Study Site, Leeds, United Kingdom

Open Label Study to Evaluate the Safety and Efficacy of Lenalidomide With MOR00208 in Patients With R-R DLBCL

Phase 2
Completed
Conditions
Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2015-03-26
Last Posted Date
2023-10-23
Lead Sponsor
MorphoSys AG
Target Recruit Count
81
Registration Number
NCT02399085
Locations
🇺🇸

CBCC Global Research, Inc. at Comprehensive Blood and Cancer Center, Bakersfield, California, United States

🇵🇱

Szpital Wojewodzki Nr 1 im. Fryderyka Chopina w Rzeszowie, Rzeszow, Poland

🇺🇸

Cancer Care - Torrance Memorial Physician Network, Redondo Beach, California, United States

and more 54 locations

Study of Fc-Optimized Anti-CD19 Antibody (MOR00208) to Treat B-cell Acute Lymphoblastic Leukemia(B-ALL)

Phase 2
Terminated
Conditions
Acute Lymphoblastic Leukemia
Interventions
Drug: MOR00208 (formerly Xmab5574)
First Posted Date
2012-09-13
Last Posted Date
2018-02-22
Lead Sponsor
MorphoSys AG
Target Recruit Count
22
Registration Number
NCT01685021
Locations
🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

🇺🇸

University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

🇺🇸

St. Jude Children's Research Hospital, Memphis, Tennessee, United States

Study of Fc-Optimized Anti-CD19 Antibody (MOR00208) to Treat Non-Hodgkin's Lymphoma (NHL)

Phase 2
Completed
Conditions
Non-Hodgkin Lymphoma
Interventions
Drug: MOR00208 (formerly Xmab 5574)
First Posted Date
2012-09-13
Last Posted Date
2023-11-07
Lead Sponsor
MorphoSys AG
Target Recruit Count
92
Registration Number
NCT01685008
Locations
🇪🇸

Morphosys Research Site, Sevilla, Spain

🇪🇸

MorphoSys Research Site, Madrid #3, Spain

🇮🇹

Morphosys, Genova, Italy

Phase Ib Study to Evaluate MOR103 in Multiple Sclerosis

Phase 1
Completed
Conditions
Multiple Sclerosis
Interventions
Biological: MOR103
Other: Placebo
First Posted Date
2012-01-25
Last Posted Date
2014-11-21
Lead Sponsor
MorphoSys AG
Target Recruit Count
32
Registration Number
NCT01517282
Locations
🇬🇧

Morhosys Investigative Site, Manchester, United Kingdom

🇬🇧

MorphoSys Investigative Site, Nottingham, United Kingdom

🇵🇱

Morphosys Investigative Site, Poznan, Poland

A Phase 1/2a Study of Human Anti-CD 38 Antibody MOR03087 (MOR202) in Relapsed/Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2011-08-22
Last Posted Date
2021-11-16
Lead Sponsor
MorphoSys AG
Target Recruit Count
91
Registration Number
NCT01421186
Locations
🇦🇹

AKH (Allgemeines Krankenhaus der Stadt Wien), Abteilung für Klinische Onkologie, Universitätsklinik für Innere Medizin I, Vienna, Austria

🇩🇪

Medizinische Klinik II, Abt. Hämatologie, Onkologie,, Tübingen, Germany

🇩🇪

Universitätsklinikum Würzburg, Medizinische Klinik und Poliklinik II, Studienambulanz für Hämatologie/Onkologie und Infektiologie, Würzburg, Germany

and more 7 locations
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