Reversal of rocuronium with neostigmine or sugammadex in high risk elderly patients: prospective randomized investigation of postoperative outcome

Phase 4

Recruiting

• Conditions: Reversal of rocuronium induced neuromuscular block in high risk elderly patients; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12614000108617
• Lead Sponsor: Thomas Ledowski

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Patients scheduled for elective or urgent (non-emergency) surgery ASA risk category 3 or 4, greater than or equal to 75 years of age, paralysed with rocuronium and extubated at the end of surgery.

Exclusion Criteria

Emergency (equals immediate) surgery, incapacity to consent to study participation, aspiration/significant atelectasis or active pneumonia within 7 preoperative days, planned to remain intubated at the end of surgery, all cardio-thoracic patients and all patients with significant chest trauma, contraindication to one of the study drugs or rocuronium, known severe neuropathy or myopathy affecting airway maintenance, breathing and neuromuscular monitoring, history of stroke with ongoing paresis, sepsis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified