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T-cell-immunity During Standard Radiotherapy in Localised Prostate Cancer

Completed
Conditions
Prostate Cancer
Registration Number
NCT01376674
Lead Sponsor
University Hospital Tuebingen
Brief Summary

Immunological effects of radiotherapy have been described before, but not evaluated in a time-dependant manner.

In order to identify a possible time frame for combination therapies, white blood cells are isolated of samples taken at different time points before during and after standard radiotherapy in patients with localised prostate cancer. The overall activity of the T-cell-system as well as tumor-specific T-cell-response are evaluated.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
22
Inclusion Criteria
  • Localised prostate cancer (node negative)
  • definitive radiotherapy
  • informed consent
Exclusion Criteria
  • medication including steroids or immunosuppressants

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
T-cell-immunity in time-courseDuring and 3-6 months after radiotherapy
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Radiation Oncology

🇩🇪

Tuebingen, Germany

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