Active after Stroke

Completed

Conditions: Cerebrovasculair accident (CVA) stroke
10007963
10047075

Registration Number: NL-OMON45278

Lead Sponsor: Hogeschool Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

* Stroke according to the WHO definition
* Age over 18
* Able to walk 10 m with supervision (Functional Ambulation Categories * 3)
- Be close to completion of the in-patient rehbailitation stay (for patients in the Hoogstraat)

Exclusion Criteria

* Severe cognitive disorder (Mini Mental State Examination <24 points)
* Severe communicative disorder (Utrecht Communication State < 4 points)
* Be a recurrent faller, defined as more than two falls in a six*month period. Falls are defined as *an unexpected event in which the participants come to rest on the ground, floor, or lower level.*
- contraindication for maximal exercise test, such as severe cardiovasculair disease.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p> The primary outcome is the ventilatory anaerobic threshold (VAT). The VAT will<br /><br>be determined as the averages from two independent raters. The VAT can be<br /><br>determined by (1) the point where the V'E/V'O2 reaches its minimum or starts to<br /><br>increase without an increase in the V'E/V'CO2; (2) the point at which the<br /><br>partial pressure of end-tidal oxygen tension (PETO2) reaches a minimum or<br /><br>starts to increase without a decline in the partial pressure of end-tidal<br /><br>carbon dioxide tension (PETCO2); and, (3) the point of deflection of<br /><br>V'CO2versus V'O2 (V-slope method). Oxygen uptake during the ST is assessed<br /><br>with the Cortex Metamax B3 (Cortex Biophysik GmbH, Leipzig, Germany) measuring<br /><br>gas exchange while subjects perform the ST. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>VO2max (ml.kg-1.min-1), defined as a plateau in VO2 or a Respiratory Exchange<br /><br>Rate (RER) of 1.05 for 50-64 year olds and RER 1.0 for those 65 years and<br /><br>older for both males and females as recommended by Edvardsen et al.<br /><br>in addition we will determine the respiratory compensation point or secondary<br /><br>ventilatory threshold (RCP). The RCP can be determined by: (1) the minimal<br /><br>value or nonlinear rise of V'E/V'CO2; (2) the point that PETCO2 starts to<br /><br>decline; and (3) the point of deflection of V'E versus V'CO2.<br /><br><br /><br>time walked during the test, measured by stopwatch<br /><br>adverse events during the test</p><br>