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临床试验/ISRCTN76149273
ISRCTN76149273
进行中(未招募)
未知

GASTROenteritis: Intravenous and oral rehydration of children with Severe Acute Malnutrition

Imperial College, London0 个研究点目标入组 336 人2018年8月8日

概览

阶段
未知
干预措施
未指定
疾病 / 适应症
未指定
发起方
Imperial College, London
入组人数
336
状态
进行中(未招募)
最后更新
2年前

概览

简要总结

暂无简介。

注册库
who.int
开始日期
2018年8月8日
结束日期
2024年10月31日
最后更新
2年前
研究类型
Interventional
性别
All

研究者

入排标准

入选标准

  • Severe dehydration \- Stratum A:
  • 1\. Aged 60 days to 12 years
  • 2\. Severe malnutrition defined as any of the following: Mid\-upper arm circumference (MUAC) \<11\.5 cm, weight for height Zscore (\< \-3SD), or signs of kwashiorkor
  • 3\. Gastroenteritis, defined as \> 3 loose stools per day
  • 4\. Signs of severe dehydration, defined (as per WHO definition) as at least one of the following: unable to drink, Alert Voice Pain Unresponsive scale (AVPU) \< A, sunken eyes, reduced skin pinch (\>2 seconds) or inability to take or retain oral fluids, and/or shock (defined as patient with cold peripheries, weak and fast pulse and capillary refill time \> 3 seconds)
  • Moderate/some dehydration \- Stratum B:
  • 1\. Aged 60 days to 12 years
  • 2\. Severe acute malnutrition criteria, complicated by dehydrating diarrhoea (defined as \> 3 loose stools per day)
  • 3\. Some to moderate dehydration or completing management of severe dehydration. Some to moderate dehydration defined as two of the following: restlessness, irritability, thirst, sunken eyes or skin pinch goes back slowly

排除标准

  • 1\. Diarrhoea lasting more than 14 days
  • 2\. Known congenital or rheumatic heart disease
  • 3\. Refusal of consent

结局指标

主要结局

未指定

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