Association Between Post-operative Anemia and Mortality After Valvular Heart Surgery

Active, not recruiting

• Conditions: Patients Undergoing Valvular Heart Surgery

• Registration Number: NCT06647758
• Lead Sponsor: Yonsei University

Brief Summary

The investigators aimed to evaluate whether postoperative anemia can predict 1-year mortality after valvular heart surgery independent of preoperative anemia. Patients who underwent valvular heart surgery were divided into four groups according to whether or not they had preoperative and postoperative anemia. Postoperative one-year mortality, as well as overall mortality and a composite of death and heart failure requiring hospitalization, was investigated according to the groups, adjusted by confounders.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-22
• Status Verified: 2024-10
• Study First Submitted: 2024-10-13
• Study First Submitted QC: 2024-10-16
• Last Update Submitted: 2024-10-16
• Study First Posted: 2024-10-18
• Last Update Posted: 2024-10-18
• Primary Completion: 2025-07-21
• Study Completion: 2025-07-21

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• Patients who underwent valvular heart surgery between January 2016 and July 2023 at Severance Cardiovascular Hospital of Yonsei University Health System.

Exclusion Criteria

• patients who underwent only pulmonary valve surgery
• those with missing hemoglobin values at 2months after the surgery, due to loss of follow up or death.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative 1-year mortality	One year after valvular heart surgery	The investigators assessed all-cause mortality during one year after valvular heart surgery and evaluated its association with preoperative and postoperative anemic status.

Secondary Outcome Measures

Name	Time	Method
overall mortality	postopeartive one-year	The investigators assessed overall mortality during the follow-up period and a composite of death and congestive heart failure (CHF) requiring rehospitalization during the postoperative one-year and evaluated their associations with preoperative and postoperative anemic status.
composite of death and congestive heart failure (CHF) requiring rehospitalization	postopeartive one-year	The investigators assessed overall mortality during the follow-up period and a composite of death and congestive heart failure (CHF) requiring rehospitalization during the postoperative one-year and evaluated their associations with preoperative and postoperative anemic status.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine and Anesthesia; 🇰🇷 Seoul, Korea, Republic of