Investigating Non-invasive Brain Stimulation to Enhance CBT in Intensive Treatment-seeking Patients With OCD

Rogers Behavioral Health1 site in 1 country20 target enrollmentMarch 18, 2024

ConditionsObsessive-Compulsive Disorder

Overview

Phase: N/A
Intervention: Not specified
Conditions: Obsessive-Compulsive Disorder
Sponsor: Rogers Behavioral Health
Enrollment: 20
Locations: 1
Primary Endpoint: Change in Quick Inventory of Depressive Symptomology from admission to discharge
Status: Withdrawn
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on patient-reported outcomes. The investigator hypothesize that patients who receive active stimulation will experience greater improvement in OCD symptoms than those who receive sham stimulation.

Registry

clinicaltrials.gov

Start Date

March 18, 2024

End Date

December 11, 2024

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Rogers Behavioral Health

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Primary diagnosis of Obsessive-Compulsive Disorder (OCD)
•Resident of state of Wisconsin
•Enrolled in OCD Intensive Outpatient Program (IOP) at Rogers Behavioral Health in Oconomowoc, WI
•Ability to communicate effectively using written and spoken English

Exclusion Criteria

•Metal in the body of any kind (e.g., braces, pacemakers, metal plates or screws, intracranial electrodes, implanted devices/defibrillators, prostheses)
•Currently taking medication that reduces seizure threshold (e.g., clomipramine)
•Cranial pathologies (e.g., holes, plates)
•History of seizure or black-out concussion
•Pregnancy
•Previous treatment at Rogers Behavioral Health

Outcomes

Primary Outcomes

Change in Quick Inventory of Depressive Symptomology from admission to discharge

Time Frame: Up to 12 weeks

Change in Yale-Brown Obsessive-Compulsive Scale - Self-Report from admission to discharge

Time Frame: Up to 12 weeks

Secondary Outcomes

Change in Quality of life enjoyment and satisfaction questionnaire - short form from admission to discharge(Up to 12 weeks)
Change in Subjective units of distress from admission to discharge(Up to 12 weeks)
Change in Obsessive-Compulsive Inventory-Revised from admission to discharge(Up to 12 weeks)
Number of treatment days between admission and discharge(Up to 12 weeks)
Change in Intolerance of uncertainty scale from admission to discharge(Up to 12 weeks)