Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Elevated level of oxidative stress
研究概览
简要总结
The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.
The main questions it aims to answer are:
- is there any association between specific parameters of pregnancy, socio-demographic characteristics and laboratory analyses with an increased level of oxidative stress
- is there any association between type of anesthesia for ceasarean section with an increased level of oxidative stress
Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).
Researchers will compare patients that received general anesthesia with patients under spinal regional anesthesia to see if there is any difference in level of oxidative stress measured by laboratory parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •ASA status I and II
排除标准
- •ASA status III and IV
- •Emergency C section
结局指标
主要结局
Elevated level of oxidative stress
时间窗: 2 hours after C section
We will measure enzymes of oxidative stress before cesarean section, during cesarean section and after cesarean section.
次要结局
- Level of cortisol(2 hours after C section)
- Lactate level(2 hours after C section)
研究者
Marina Boboš
Principal Investigator
University Clinic Dr Dragisa Misovic-Dedinje