Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obstetric Anesthesia Problems
- Sponsor
- University Clinic Dr Dragisa Misovic-Dedinje
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Elevated level of oxidative stress
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.
The main questions it aims to answer are:
- is there any association between specific parameters of pregnancy, socio-demographic characteristics and laboratory analyses with an increased level of oxidative stress
- is there any association between type of anesthesia for ceasarean section with an increased level of oxidative stress
Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).
Researchers will compare patients that received general anesthesia with patients under spinal regional anesthesia to see if there is any difference in level of oxidative stress measured by laboratory parameters.
Investigators
Marina Boboš
Principal Investigator
University Clinic Dr Dragisa Misovic-Dedinje
Eligibility Criteria
Inclusion Criteria
- •ASA status I and II
Exclusion Criteria
- •ASA status III and IV
- •Emergency C section
Outcomes
Primary Outcomes
Elevated level of oxidative stress
Time Frame: 2 hours after C section
We will measure enzymes of oxidative stress before cesarean section, during cesarean section and after cesarean section.
Secondary Outcomes
- Level of cortisol(2 hours after C section)
- Lactate level(2 hours after C section)