Assessment of the quality of the automatic stimulus electrodiagnosis test to detect diseases in peripheral nerves
Not Applicable
Recruiting
- Conditions
- PolyneuropathiesCraniocerebral Trauma
- Registration Number
- RBR-6rtdrn
- Lead Sponsor
- Paulo Eugênio Silva
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Healthy. Individuals with no history of neuromuscular or orthopedic disease; Intensive care unit. Patients with traumatic brain injury;
Sedated patients with at least 6 days of invasive mechanical ventilation; Participants aged between 18 and 60 years.
Exclusion Criteria
Healthy. Pregnant women; Individuals with skin lesions in the area to be assessed; Intensive care unit. Pregnant women; Patients with skin lesions and or fractures in the area to be assessed; Use of neuromuscular blocker on the day of the assessment; Patients with brain death.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method a) Reproducibility of the stimulus electrodiagnosis test (SET) manual and automated;<br><br>;b) SET sensitivity and specificity for the diagnosis of critical illness polyneuromyopathy to ultrasound as the gold standard.
- Secondary Outcome Measures
Name Time Method a) Association and collinearity between chronaxia and intensity-duration curve with clinical characteristics (physiological severity and trauma score at admission (SAPS III and ISS), physiological severity score at the day of assessment (SOFA), presence of sepsis, use of vasopressor drugs, blood glucose, use of corticosteroids, etc.), as well as, with clinical outcomes (duration of mechanical ventilation, length of ICU stay, mortality, etc.).<br><br>;b) Association between the quality of evoked contraction and two points of pulse width in the intensity-duration curve (500 us and chronaxia);<br>