Ontogenic Measurement of Plasma Oxytocin in Typically Developing Boys Using Extracted and Unextracted EIA Methods
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Plasma Oxytocin Levels
研究概览
简要总结
Measuring basal levels of plasma oxytocin in individuals with typical development across childhood and adolescence using both extracted and unextracted EIA methods.
详细描述
Measuring basal levels of plasma oxytocin in individuals with typical development across childhood and adolescence using both extracted and unextracted EIA methods. This study is necessary since there is great variability in reported plasma oxytocin in typically developing children from other studies as well as up to 1000 fold variability in such levels using different assay procedures. Further existing studies have not clearly described variation in levels with age. all samples will be taken in the afternoon.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 3 Years 至 17 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Between 3 and 17 years old, inclusive
- •Consent of parent or guardian.
排除标准
- •Exclusion Criteria for Healthy Control Participants:
- •Female gender
- •Evidence of a mental health diagnosis
- •Evidence of significant medical condition (ie: renal, cardiovascular or genetic disease)
- •First degree family member with an ASD diagnosis
结局指标
主要结局
Plasma Oxytocin Levels
时间窗: Baseline oxytocin level at visit 1 (time zero)
20 children in each of 3 age cohorts 3-6, 7-12, and 13-17 will participate. Plasma oxytocin levels will be taken at the screening appointment.
次要结局
- Inflammatory markers(at single time point)
研究者
Linmarie Sikich, MD
Associate Professor of Psychiatry
University of North Carolina, Chapel Hill