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Oxytocin Levels in Typically Developing Boys

Completed
Conditions
Healthy Boys
Registration Number
NCT02006381
Lead Sponsor
University of North Carolina, Chapel Hill
Brief Summary

Measuring basal levels of plasma oxytocin in individuals with typical development across childhood and adolescence using both extracted and unextracted EIA methods.

Detailed Description

Measuring basal levels of plasma oxytocin in individuals with typical development across childhood and adolescence using both extracted and unextracted EIA methods. This study is necessary since there is great variability in reported plasma oxytocin in typically developing children from other studies as well as up to 1000 fold variability in such levels using different assay procedures. Further existing studies have not clearly described variation in levels with age. all samples will be taken in the afternoon.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
60
Inclusion Criteria
  • Between 3 and 17 years old, inclusive
  • Consent of parent or guardian.
Exclusion Criteria
  • Exclusion Criteria for Healthy Control Participants:
  • Female gender
  • Evidence of a mental health diagnosis
  • Evidence of significant medical condition (ie: renal, cardiovascular or genetic disease)
  • First degree family member with an ASD diagnosis

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Plasma Oxytocin LevelsBaseline oxytocin level at visit 1 (time zero)

20 children in each of 3 age cohorts 3-6, 7-12, and 13-17 will participate. Plasma oxytocin levels will be taken at the screening appointment.

Secondary Outcome Measures
NameTimeMethod
Inflammatory markersat single time point

C reactive protein and cytokine panel

Trial Locations

Locations (1)

University of North Carolina Chapel Hill

🇺🇸

Chapel Hill, North Carolina, United States

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