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TetraGraph in Rocuronium Infusions

Not Applicable
Not yet recruiting
Conditions
Surgery
Interventions
Device: TetraGraph
Registration Number
NCT06472284
Lead Sponsor
Joseph D. Tobias
Brief Summary

This is a prospective, non-blinded study to evaluate rocuronium infusion requirements using the TetraGraph Neuromuscular Transmission Monitor during surgical procedures in patients less than 18 yrs. of age.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Patients less than 18 years of age
  • American Society of Anesthesiologists classification (ASA) 1-4
  • Patients undergoing a surgical procedure with general anesthesia and requiring the continuous administration of rocuroniuim
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Exclusion Criteria
  • Patients less than 28 days old
  • Patients with history of a progressive or degenerative peripheral neurologic or neuropathic disorder
  • Patients undergoing a surgical procedure in which neuromuscular blockade is not required
  • Edematous patients
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Rocuronium infusionTetraGraphPatients who are scheduled for elective, urgent or emergent surgery requiring the continuous infusion of the neuromuscular blocking agent, rocuronium.
Primary Outcome Measures
NameTimeMethod
EMG changesDuring the surgery (2-8 hrs.)

Changes in the amplitude of the evoked response of the muscles

Maximum dose of rocuroniumDuring the surgery (2-8 hrs.)

The maximum dose of rocuronium administered by a continuous infusion to maintain one twitch of the train of four (TOF)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Nationwide Children's Hospital

🇺🇸

Columbus, Ohio, United States

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