Comparison of the effect of intraoperative infusion of sub-anesthetic ketamine and dexmedetomidine on the postoperative cognitive function in patients undergoing modified radical mastectomy – A Randomized controlled trial. - NI

Jawaharlal Institute of Postgraduate Medical Education and Research0 sites0 target enrollmentTBD

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Not specified
Sponsor: Jawaharlal Institute of Postgraduate Medical Education and Research
Status: Not yet recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Investigators

Sponsor

Jawaharlal Institute of Postgraduate Medical Education and Research

Eligibility Criteria

Inclusion Criteria

•1\.Adult patients aged 18 to 65 years undergoing modified radical mastectomy.
•2\.American society of Anesthesiologists (ASA) status 1\-3

Exclusion Criteria

•1\.History of dementia or Montreal cognition assessment score less than 26
•2\.severe audio\-visual impairments and illiterate patients.
•3\.Allergy to any of the drugs used in the study including ketamine and dexmedetomidine.
•4\.patients receiving regional blocks for postoperative analgesia for MRM
•5\. ischemic heart disease and uncontrolled hypertension, severe pulmonary disease, heart failure (New York Heart Association class \> II).
•6\. History of known psychiatric/ neurodegenerative disorder
•7\. Hepatic or renal impairment.
•8\. patients taking sedatives, antidepressants and glucocorticoids

Outcomes

Primary Outcomes

Not specified

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