Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal

Second Affiliated Hospital, School of Medicine, Zhejiang University1 site in 1 country5 target enrollmentMarch 20, 2022

ConditionsEpilepsy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Epilepsy
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Enrollment: 5
Locations: 1
Primary Endpoint: Phonetic Feature Encoding in Human Superior Temporal Gyrus
Status: Active, not recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.

Registry

clinicaltrials.gov

Start Date

March 20, 2022

End Date

December 25, 2023

Last Updated

3 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Responsible Party

Principal Investigator

Hemmings Wu

Neurosurgeon, Assistant Professor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Eligibility Criteria

Inclusion Criteria

•Patients with focal refractory epilepsy also need preoperative evaluation with SEEG

Exclusion Criteria

•History of major depression or psychiatric disorders and medication that causes symptoms of psychiatric disorders
•Patients with severe cognitive impairment (MMSE score ≤15), unable to complete the language function test