Cognitive Impairments in Children With Epilepsy

Completed

• Conditions: Epilepsy Syndrome

• Registration Number: NCT05097742
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Since the proportion of language and attentional difficulties in patients with epilepsy is recognized, both in the literature and in the clinical experience of practitioners, it is appropriate to propose a complete speech-language assessment of oral language and attention.This study investigates these impairments through the taking of specific tests.

The general objective of this study is to observe possible oral language and attention disorders in children with epilepsy, by age and etiology of epilepsy.

The objective of this work is to study therapeutic apheresis (including plasma exchange and immunoadsorption) among french neuropediatric tertiary centers and to prove that this treatment modality is effective and well tolerated in pediatric neurology diseases.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-15
• Study First Submitted: 2021-10-27
• Study First Submitted QC: 2021-10-27
• Study First Posted: 2021-10-28
• Primary Completion: 2022-02-01
• Study Completion: 2022-02-20
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-11
• Last Update Posted: 2022-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Score in the different tests assessing oral language	day 1	Test assessing oral language : * Oral naming of images; * Oral designation of images; * Morphosyntactic comprehension test; * Syntactic production test; The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : "pathological" zone Class 2 = 7 to 20 percentiles : "fragile" zone / "weak" zone Class 3 = 21 to 38 percentiles : "low standard" zone Class 4 = percentiles 39 to 62 : "median standard" zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : "higher standard" zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level.

Secondary Outcome Measures

Name	Time	Method
Score in the different tests assessing attention	day 1	Tests assessing attention : * Visual attention test; * Auditive attention test; The scores obtained in the various tests are organized into 7 classes: Class 1 = percentiles less than 7 : "pathological" zone Class 2 = 7 to 20 percentiles : "fragile" zone / "weak" zone Class 3 = 21 to 38 percentiles : "low standard" zone Class 4 = percentiles 39 to 62 : "median standard" zone / expected average results for age or grade level Class 5 = 63 to 80 percentiles : "higher standard" zone Classes 6 and 7 = respectively 81 to 93 percentiles and percentiles greater than 93 : zone with results well above the norm for age or grade level.

Trial Locations

Locations (1)

Uh Montpellier; 🇫🇷 Montpellier, France