Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity

Completed

• Conditions: Specific Language Impairment
• Interventions: Diagnostic Test: EEG was recorded by EEG Machines

• Registration Number: NCT04141332
• Lead Sponsor: Mansoura University Hospital

Brief Summary

The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.

Detailed Description

This study concentrates on the impact of epileptiform activity for childhood epilepsy on the speech and language disturbances in addition to the associated social, cognitive and intellectual dysfunctions.

Study Timeline

• Study Start: 2018-02-01
• Primary Completion: 2019-01-01
• Study Completion: 2019-03-01
• Status Verified: 2019-10
• Study First Submitted: 2019-10-23
• Study First Submitted QC: 2019-10-24
• Last Update Submitted: 2019-10-24
• Study First Posted: 2019-10-28
• Last Update Posted: 2019-10-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• 80 children were suffering from specific language impairment
• 80 healthy children with age and sex match control group.

Exclusion Criteria

• Previous history of perinatal hypoxic-ischemic damage
• meningitis or encephalitis
• motor weakness
• hearing disorders
• IQ below seventy
• CP, social deprivation
• autism and
• psychiatric disorders .

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	EEG was recorded by EEG Machines	80 Patient
Group 2	EEG was recorded by EEG Machines	80 Control subject

Primary Outcome Measures

Name	Time	Method
EEGs finding	24-48 hours	EEGs finding were defined according to the followings "Normal: within the range of frequency and amplitude distribution." "Epileptiform: Describes transient background activity with a characteristic spikes, sharp waves, spike-slow wave or sharp-slow wave complexes of focal or generalized distribution".; "Abnormal non-epileptiform: deviations from normal in terms of background frequency patterns, usually in the form of excessive slow activity".

Trial Locations

Locations (1)

Mansoura University Hospital; 🇪🇬 Mansoura, Dakahlia, Egypt