Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mansoura University Hospital
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- EEGs finding
Study Overview
Brief Summary
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
Detailed Description
This study concentrates on the impact of epileptiform activity for childhood epilepsy on the speech and language disturbances in addition to the associated social, cognitive and intellectual dysfunctions.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 3 Years to 6 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •80 children were suffering from specific language impairment
- •80 healthy children with age and sex match control group.
Exclusion Criteria
- •Previous history of perinatal hypoxic-ischemic damage
- •meningitis or encephalitis
- •motor weakness
- •hearing disorders
- •IQ below seventy
- •CP, social deprivation
- •autism and
- •psychiatric disorders .
Outcomes
Primary Outcomes
EEGs finding
Time Frame: 24-48 hours
EEGs finding were defined according to the followings "Normal: within the range of frequency and amplitude distribution." "Epileptiform: Describes transient background activity with a characteristic spikes, sharp waves, spike-slow wave or sharp-slow wave complexes of focal or generalized distribution". "Abnormal non-epileptiform: deviations from normal in terms of background frequency patterns, usually in the form of excessive slow activity".
Secondary Outcomes
No secondary outcomes reported
Investigators
Ahmed Esmael
Assistant Prof of Neurology
Mansoura University Hospital