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Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal

Not Applicable
Active, not recruiting
Conditions
Epilepsy
Interventions
Behavioral: Speech
Device: Stereoelectroencephalography
Registration Number
NCT05776745
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Brief Summary

Based on stereoelectroencephalography model in the treatment of epilepsy patients, this study conducted language-related experimental studies without interfering with normal monitoring treatment. Meanwhile, voice data and intracranial electrophysiological data were collected for analysis. To study the mechanism related to the language function of patients, try to establish a model to decode the intracranial electrophysiological data related to language.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
5
Inclusion Criteria
  • Patients with focal refractory epilepsy also need preoperative evaluation with SEEG
Exclusion Criteria
  • History of major depression or psychiatric disorders and medication that causes symptoms of psychiatric disorders
  • Patients with severe cognitive impairment (MMSE score ≤15), unable to complete the language function test

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
EpilepticSpeechEpileptic with stereoelectroencephalography
EpilepticStereoelectroencephalographyEpileptic with stereoelectroencephalography
Primary Outcome Measures
NameTimeMethod
Phonetic Feature Encoding in Human Superior Temporal Gyrusthrough study completion, an average of 1 year

Phonetic Feature Encoding in Human Superior Temporal Gyrus

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Zhejiang University School of Medicine Second Affiliated Hospital

🇨🇳

Hangzhou, Zhejiang, China

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