Effect of Uraimathirai in Increasing children Immunity
- Conditions
- Health Condition 1: J069- Acute upper respiratory infection,unspecified
- Registration Number
- CTRI/2017/06/008723
- Lead Sponsor
- CENTRAL COUNCIL FOR RESEARCH IN SIDDHA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Children of either gender aged 6 MONTHS to 6 Years with a history of recurrent URTIs and presenting with URTI at hospital treatment.
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The definition used for recurrent URTIs was three or more such episodes during the last 12 months.
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The current episode required for study eligibility was
Defined by the presence of at least two of the following
Rhinitis
Pharyngitis
cough
hoarseness,
Temperature More than 38.5�°C,
Prescription of an antibiotic for a URTI, occurring after an asymptomatic Period of at least 1 week without antibiotics
occurrence of otitis media and/or sinusitis and/or
infection of the lower respiratory tract (ie, bronchitis, pneumonia)and/or proven group A streptococcal angina at the enrollment
Further main exclusion criteria were allergic asthma,
significant systemic disease (eg, hepatic and/or
renal disease, malignancy), immune system disorders, suspected
Malabsorption, major surgical procedure within 3 months of commencement of the study
recent immunosuppressive or immunostimulant therapy, or corticosteroids.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in Recurrence of Resp Infections <br/ ><br> <br/ ><br>Clinical Improvement <br/ ><br> <br/ ><br>No Antibiotic treatment <br/ ><br> <br/ ><br>Increase in Anti bodies IgA/IgG <br/ ><br> Decrease in Phagocytosis <br/ ><br>Timepoint: 6 months <br/ ><br>
- Secondary Outcome Measures
Name Time Method Safety of trial drugTimepoint: 6 months