The effect of vitamin D supplementation at diagnosis of pneumonia upon response to treatment

Completed

• Conditions: Pneumonia; Respiratory

• Registration Number: ISRCTN61245920
• Lead Sponsor: Aga Khan Health Services Afghanistan (Afghanistan)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-03-21
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 450

Inclusion Criteria

Any child, living in the defined areas of Kabul (within the catchment area of the Maywand Teaching Hospital), between 1 week and 18 complete months of age.

Exclusion Criteria

1. >8 hours after the start of hospital antibiotics treatment
2. Living outside of the study areas of Kabul and child?s families expect to move away within the next 3 months
3. If the child has been diagnosed with clinical rickets or known to have received a course of high dose vitamin D treatment in the past 3 months (doses as high as 300,000 IU are used routinely in India and Pakistan, and thus rarely, some recently returned returnee children may have recently received such doses)
4. If have symptoms of very severe pneumonia (according to IMCI definitions of very severe pneumonia) or other illnesses as the major diagnosis occurring at the same time as pneumonia, such as meningitis, major heart or renal defect, active measles, severe malnutrition requiring separate medical treatment, and suspected tuberculosis
5. Child with severe diarrhoea or vomiting
6. Wheeze at the time of diagnosis (if wheeze develops later the child continues to be in the study)
7. Caretakers do not give consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified