NL-OMON49105招募中3 期
Preventing Oxidative stress-induced ischemic injury and systemic inflammation complications during and after invasive cardiac surgery with Alkaline Phosphatase (APPIRED III) - RESCAP to prevent complications in heart surgery
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •A potential subject must meet all of the following criteria to participate in the study:
- •1. greater than 21 years of age (legal adult in Singapore)
- •2. Undergoing cardiac surgery with planned cardiopulmonary bypass
- •3. EUROSCORE II greater than or equal 3
- •4. Ability to provide informed consent (not incapacitated)
排除标准
- •Any subjects meeting the following criteria at baseline will be excluded:
- •1. Already on renal replacement therapy
- •2. Patients with chronic kidney disease defined as urinary albumin excretion of >=30 mg/day, or equivalent or estimated glomerular filtration rate lower than 60 ml/min/1.73 m2 ( CKD stage > 2)
- •3. Patients who are pregnant
- •4. Concurrent enrolment in another clinical trial
- •5. Known allergic reaction to bovine alkaline phosphatase
研究者
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