The effect of medicinal plants on the leishmaniosis

Phase 2

Recruiting

Conditions: Cutaneous leishmaniasis.
Cutaneous leishmaniasis
B55.1

Registration Number: IRCT20191221045845N1

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 132

Inclusion Criteria

Proof of cutaneous leishmaniasis through smear
The patients should not be less than 6 years old and not more than 60 years old
The lesion size should be less than 3 cm
The duration of the illness is less than 12 weeks
No lesion on the face
Not having any other anti-leishmaniasis medication in the past 4 weeks
Don't be pregnant or breastfeeding
Do not have severe skin disease such as eczema, psoriasis or chronic dermatitis of unknown origin
Has no serious, chronic or malignant disease and is not under chemotherapy treatment
Has 4 or less lesions in the body
No travel history 6 months ago

Exclusion Criteria

The type of cutaneous leishmaniasis may be complicated, with complications such as a patient with mucosal leishmaniasis
Having 5 lesions and more
Lesions greater than 3 cm
Subcutaneous nodules
Regional adenopathy larger than 1 cm
People with immunodeficiency
Children under 6 years
Women in Lactation and Pregnancy
sporotrichoid leishmaniasis or satellite lesions
Patients with ulcers on the face
Patients with a history of drug allergy to antimony compounds
Patients who have had more than three months since their first skin lesions appeared
Patients who have used any method of treatment for cutaneous leishmaniasis during the past month
Patients with a history of travel to other areas of leishmaniasis in the past 6 months as well as those of urban leishmaniasis

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eishmaniasis lesion area. Timepoint: Before treatment and then every week until healing or the eighth week. Method of measurement: Mathematical calculations with mm-square scale.

Secondary Outcome Measures