Vitamin E in onoxaliplatin-induced neuropathy preventio
Not Applicable
- Conditions
- Condition 1: cancer of colorectal. Condition 2: pripheral neuropathy.Malignant neoplasm of rectosigmoid junctionDrug-induced polyneuropathy
- Registration Number
- IRCT2015030621350N1
- Lead Sponsor
- Vice Chancellor for research of Isfahan of University Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Inclusion criteria : 18 to 75 years of age ; diagnosed with colorectal cancer ; scheduled to receive oxaliplatin-based regimens (FOLFOX 4) ; had more than 6 month life expectancy
exclusion criteria : previous history of peripheral neuropathy ; symptomatic peripheral neuropathy at entry into the study ; received other chemotherapy regimens ; currently receiving anticoagulants ; platelet aggregation inhibitors ; opioids ; anticonvulsants ; tricyclic antidepressants ; previous history of hemorrhagic stroke
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Peripheral neuropathy. Timepoint: before study and then 3 months later. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method