Determining the association of response rate to Intravitreal injection of bevacizumab and macular vessel density in patients with diabetic macular edema using optical coherence tomography angiography (OCT-A)
- Conditions
- Determining the association of response rate to Intravitreal injection of bevacizumab and macular vessel density in patients with diabetic macular edema using optical coherence tomography angiography (OCT-A) in outpatients referred to Feyz Hospital.Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edemaE08.321
- Registration Number
- IRCT20220416054548N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Age over 18 years
Having type 1 or 2 diabetes
Central macular edema based on Heidelberg's clinical examination and OCT in one or both eyes (at least 305 µm in women and 320 µm in men)
Best modified view less than or equal to 10/7
No history of laser in the patient's eye
Moderate to severe non-proliferative diabetic retinopathy with diabetic macular edema
Transparent media to the extent that it does not interfere with the quality of images and their analysis (SSI: signal strength index: 37-40)
History of retinal vascular obstructive diseases
History of intraocular injection in the last 6 months
History of intraocular and retinal laser in the affected eye in the last 12 months
Decreased vision following any ocular pathology other than diabetic retinopathy
High Myopia (= -8)
History of eye surgery in the last 6 months
Uncontrolled glaucoma (IOP = 30 mmHg despite maximal treatment)
Uncontrolled diabetes
Uncontrolled blood pressure (SBP =180 mmHg or DBP =100 mmHg
Connective tissue diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method