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Comparison of the effect of DiphenCiprone alone and DiphenCiprone with intralesional injection of platelet-rich plasma in alopecia areata

Not Applicable
Conditions
Alopecia areata.
Other alopecia areata
L63.8
Registration Number
IRCT20200130046311N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
20
Inclusion Criteria

A patient with alopecia areata whose definitive diagnosis was made on clinical or histological basis and their involvement was severe (> 50% scalp area and less than 100%).
Positive response to test with 2% Diphen Ciprone solution

Exclusion Criteria

Patients with alopecia totalis or universalis
Receive any systemic treatment during the last 6 months
Children under 18 years
Pregnant and lactating women
Immunosuppressed patient
patient with platelet dysfunction
patient with a history of injecting steroids on the site over the past month
Fever, systemic infection and local infection at the injection site

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity alopecia tool score (SALT score). Timepoint: Trichoscopic evaluation at baseline, 3 months later, 6 months later. Method of measurement: Trichoscope.
Secondary Outcome Measures
NameTimeMethod
SALT score evaluation. Timepoint: Evaluation at baseline, 3 months later, 6 months later. Method of measurement: visual evaluation.
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