Effect of Bifidobacterium on Irritable Bowel Syndrome
- Conditions
- Irritable Bowel Syndrome
- Interventions
- Drug: Placebo
- Registration Number
- NCT00737841
- Lead Sponsor
- Tohoku University
- Brief Summary
There has been no data on effect of Bifidobacterium breve on symptoms of patients with irritable bowel syndrome (IBS). We hypothesized that Bifidobacterium breve is effective on symptoms of IBS patients.
- Detailed Description
There has been no data on effect of Bifidobacterium breve on symptoms of patients with irritable bowel syndrome (IBS). We hypothesized that Bifidobacterium breve is effective on symptoms of IBS patients. IBS patients will be enrolled via advertisement. Any IBS subtypes will not be rejected. They will take either 1.0 g of Bifidobacterium breve 3 times a day or same amount of placebo for 8 weeks. IBS symptoms and allied markers will be checked before, during, and after the administration.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- Diagnosis of IBS with Rome II definition
- Diagnosis of serious diseases (both physically and mentally)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description B Placebo Placebo A Bifidobacterium breve Bifidobacterium breve
- Primary Outcome Measures
Name Time Method Adequate relief and SIBSQ 2, 0, 2, 4, 8 weeks during treatment and 4 weeks after treatment
- Secondary Outcome Measures
Name Time Method Psychometric test, bowel gas, blood, and feces. 2, 0, 2, 4, 8 weeks during treatment and 4 weeks after treatment
Trial Locations
- Locations (1)
Tohoku University Graduate School of Medicine
🇯🇵Sendai, Miyagi, Japan