Morphological and functional changes of the median nerve after neurolysis for carpal tunnel syndrome - ultrasonography of the median nerve after neurolysis for CTS

Atrium Medisch Centrum0 个研究点目标入组 100 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•1. Age > 18 years
•2. Clinical signs of carpal tunnel syndrome, as described by the AAN criteria for CTS: paresthesias, pain, swelling, weakness, or clumsiness of the hand (digit 1-4) provoked or worsened by sleep, sustained hand or arm position, or repetitive action of the hand or wrist that is mitigated by changing posture or by shaking of the hand; sensory deficits in the median innervated region of the hand; and motor deficit or hypotrophy of the median innervated thenar muscles
•3. Electrophysiological evidence of CTS (see below)
•4. Surgery is the preferred treatment modality
•5. Patients having bilateral CTS can only participate with the most affected side.
•6. Criterium for the time interval between initial exam and surgery: within 5 weeks
•7. Able to read and understand written questionnaires (in Dutch)
•8. Informed written consent

•1. Unable to follow up
•2. Prior surgery or trauma on the wrist / median nerve
•3. Previous surgery for carpal tunnel syndrome; previous surgery for CTS on the contralaterale side is not an exclusion criterium.
•4. Treatment with splints or corticosteroids the past 6 months.
•5. Clinical or electrophysiological evidence of conditions that could mimic CTS or interfere with its
•validation (cervical radiculopathy, brachial plexopathy, thoracic outlet syndrome, pronator teres syndrome, ulnar neuropathy, polyneuropathy, Raynaud*s disease, sympathic dystrophy)
•6. Underlying causes of CTS: diabetes, thyroid disease, rheumatoid arthritis, chronic renal failure
•treated by hemodialysis, space-occupying lesions a the volar wrist. A bifid median nerve of persistant median artery are no exclusion criteria.
•7. Pregnancy

发起方

Atrium Medisch Centrum