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A STUDY INTENDED TO FIND THE ADEQUACY OF VARIOS DOSES OF FENTANYL BEFORE ANAESTHESIA IN ACHIEVING DESIRED HYPOTENSIO

Not Applicable
Completed
Conditions
Health Condition 1: J324- Chronic pansinusitisHealth Condition 2: null- Patients with rhinosinusitis undergoing Functional endoscopic sinus surgery
Registration Number
CTRI/2014/03/004457
Lead Sponsor
Department of Anaesthesiology Pain Perioperative Medicine Sir Ganga Ram Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

1. ASA physical status grade I-II

2. Patients scheduled to undergo bilateral FESS involving non-fungal sinusitis under general anaesthesia (GA)

Exclusion Criteria

Uncontrolled hypertension

Hepato-renal disease

Hypersensitivity to opioids

Associated cranio-facial anomaly

Significant cardio-vascular disease

Psychiatric disorders

Pre-existing hyper-reactive airways disease

Chronic alcoholics and/or smokers

Inability to attain/sustain induced hypotension

Hyperactive response to fentanyl (apnea, hypotension

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Achievement and maintenance of intraoperative induced hypotensionTimepoint: From induction of anaesthesia to end of surgery
Secondary Outcome Measures
NameTimeMethod
1. Improvement in surgical field conditions <br/ ><br> 2. Intraoperative propofol-sparing effect <br/ ><br> 3. Frequency of intra-operative specific hypotensive supplements (if any)to anaesthesia (propofol TIVA) and analgesia (fentanyl) <br/ ><br>4. Postoperative outcome (side effects, awakening)Timepoint: From induction of anaesthesia to 24 hrs postoperatively
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