Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)

Completed

• Conditions: Supraventricular Tachycardia

• Registration Number: NCT02810561
• Lead Sponsor: Spectrum Health - Lakeland

Brief Summary

The goal of this study is twofold. First the investigators would like to determine the trajectory of troponin leaks; if it can be shown that the participants who have only minimal elevations of their repeat troponin universally decrease on the 3rd level then future patients may see significantly improved length of stay. Second, given conflicting results in the literature, the investigators would like to determine if elevated troponin levels correlate to later cardiovascular complications. These complications will be defined as Death, Myocardial Infarction, Cardiovascular intervention (such as coronary artery stenting or bypass). As the investigator is a single hospital system in this county it is uniquely positioned to be able to review this retrospectively.

Detailed Description

The investigators therefore propose retrospectively studying participants diagnosed with Supraventricular Tachycardia who had troponin(s) checked in the ED between January 1, 2012 and May 31, 2016 to allow a minimum of a year follow-up for our combined endpoint. The investigators will record the participants troponin value(s) in addition to the age, sex, race, heart rate, creatinine value. The investigators will compare the participants with positive troponins (and hopefully participants with strongly positive troponins) with those who are negative for troponin for presence of the combined end point via chart review.

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2016-04-26
• Study First Submitted QC: 2016-06-22
• Study First Posted: 2016-06-23
• Primary Completion: 2016-07
• Study Completion: 2016-07
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-15
• Last Update Posted: 2022-08-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

• Supraventricular Tachycardia with troponin elevation

Exclusion Criteria

• Other cardiac arrhythmias or conditions with increased troponin

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Troponin-I Level	6 hours after initial EKG	Measured in ng/ml

Secondary Outcome Measures

Name	Time	Method
Death/ Need for Cardiac Stent Placement or Coronary Bypass Artery Graft	6 months