Cardiovascular Assessment in Patient Recovered From COVID-19 and Recovery of Autonomic Nervous System in Association With the Severity of the Disease

Not Applicable

Completed

• Conditions: COVID-19
• Interventions: Other: Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity

• Registration Number: NCT05081362
• Lead Sponsor: IRCCS Policlinico S. Donato

Brief Summary

The goal of the study is to assess autonomic nervous system and cardiovascular controll during orthostatic challenge in 90 patients recovered from COVID-19 and devided into three groups depend on severity of the morbidity.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-07
• Study First Submitted QC: 2021-10-15
• Study Start: 2021-10-18
• Study First Posted: 2021-10-18
• Primary Completion: 2022-11-09
• Study Completion: 2022-11-09
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-23
• Last Update Posted: 2023-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 67

Inclusion Criteria

• age over 18
• spontaneous sinus rhythm
• signed informed consent

Exclusion Criteria

• no spontaneous sinus rhythm
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
COVID-mild	Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity	patient recovered from mild COVID desease
COVID-moderate	Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity	patient recovered from moderate COVID desease
COVID-severe	Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity	patient recovered from severe COVID desease

Primary Outcome Measures

Name	Time	Method
Arterial pressure measured in mmHg	6 months	Continuous measurement of the arterial pressure for 10 minutes in rest and 10 minutes in orthostatic position.
Heart rate measured in bpm	6 months	Continuous measurement of heart rate for 10 minutes in rest and 10 minutes in orthostatic position.
Respiratory frequency	6 months	Continuous measurement of respiratory frequency for 10 minutes in rest and 10 minutes in orthostatic position.

Trial Locations

Locations (1)

IRCCS Policlinico San Donato; 🇮🇹 San Donato Milanese, Milano, Italy