Comparison of 7 days versus 14 days antibiotics for patients hospitalized with non-severe kidney infectio
- Conditions
- Health Condition 1: null- Acute pyelonephritisHealth Condition 2: N390- Urinary tract infection, site notspecified
- Registration Number
- CTRI/2016/04/006810
- Lead Sponsor
- Department of Medicine Jawaharlal Institute of Postgraduate Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 54
Either sex aged >18 years, admitted for acute pyelonephritis, defined as fever of at least 38oC and at least one symptom or sign relating to the urinary tract such as flank pain, costovertebral angle tenderness, dysuria, urgency or frequency along with the microbiologic criteria (>=10 pus cells/hpf or dipstick leucocyte esterase test positive and a positive culture with >=10 5 CFU/ mL of urine). They should have improved with empirical or culture-guided antibiotic treatment and be afebrile for at least 48 hours by day 7 of antibiotic treatment.
•Catheter-associated UTI
•Recurrent UTI
•Obstructive uropathy
•Residual bladder urine >100 ml
•Acute or chronic prostatitis / prostatic abscess
•Emphysematous PN/renal or perinephric abscess
•Shock requiring vasopressors
•Altered sensorium requiring intubation (GCS score <8)
•Acute lung injury requiring mechanical ventilation
•Renal failure requiring RRT
•Clinically manifest DIC
•Pregnancy
•Any immunosuppressive treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method