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Norwegian Occipital Ischemic Stroke Study

Conditions
Ischemic Stroke
Visual Field Defect
Interventions
Other: Training with vision teacher (visual rehabilitation)
Registration Number
NCT02307981
Lead Sponsor
Haukeland University Hospital
Brief Summary

Patients who suffer an ischemic stroke in the occipital lobe often experience Visual Field defects. Visual Field defects are negatively correlated to falling, institutionalisation, rehabilitation outcome and quality of life. Patients are often not properly examined and seldom receive rehabilitation. NOR-OCCIP aims to evaluate the Natural history of Visual Field defects after occipital infarction and to determine whether rehabilitation is effective.

Detailed Description

BACKGROUND: Visual Field defects after cerebral infarction is an increasingly acknowledged problem, which has consequences for patient outcome. The aim of the Norwegian Occipital Ischemic Stroke Study (NOR-OCCIP) is to: 1.) Improve clinical diagnostics and management of visual field defects in occipital stroke. 2.) Identify and estimate the need for visual rehabilitation among patients with VFD by studying the natural course and the rate of spontaneous recovery. 3.) Study the effect of visual rehabilitation both on visual function as well as on quality of life. METHODS: Patients with acute ischemic occipital stroke on MRI are recruited from Bergen, Stavanger and Trondheim. Patients are included for a period of 1.5 years, starting August 15th 2013. Patients are eligible for inclusion if \>18 years, written consent is obtained and the patient is able to co-operate to examination with autoperimetry. Within one week patients are examined by ophthalmologist after a standardized protocol including autoperimetry. During week four patients are examined by vision teacher after a standardized protocol and a structured interview on vision specific function and quality of life (VFQ-25) is conducted by a study nurse via telephone. If visual rehabilitation is provided by the municipality in which the patient lives, the patient will be referred to such. Eye examination including autoperimetry, vision teacher assessment and VFQ-25 is repeated after 6 months. All patients will be registered in the national stroke registry, and the following variables will be analysed: Demographic variables, lifestyle factors, clinical status at admission (scores on NIHSS), clinical status at discharge and 3 months post-stroke (scores on modified Rankin Scale). So far 62 patients have been included. Limited research exists on visual impairment after cerebral infarction. It is important to establish the natural course of visual impairment after ischemic stroke, and to evaluate the effect of visual rehabilitation.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
75
Inclusion Criteria
  • Written consent obtained,
  • age >18,
  • acute occipital infarction on brain imaging and ability to cooperate for examination with autoperimetry
Exclusion Criteria
  • Pathological processes that severely affect eyesight.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Visual field defect with vision teacherTraining with vision teacher (visual rehabilitation)Patients With occipital ischemic stroke and Visual Field defect that live in a geographical region where training With vision teacher is an available service (vision Teachers are a Limited Resource in Norway)
Primary Outcome Measures
NameTimeMethod
Visual Field defect6 months

Change in Visual Field defect as measured by autoperimetry

Secondary Outcome Measures
NameTimeMethod
Change in Visual function6 months

Change in Visual function as measured by standardized mapping by vision teacher according to pre-specified protocol

Quality of life and self reported Visual function6 months

Vision specific QoL and function as measured by VFQ-25

NIHSSOne week

Trial Locations

Locations (2)

Stavanger University Hospital

🇳🇴

Stavanger, Rogaland, Norway

St. Olav University Hospital

🇳🇴

Trondheim, Norway

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