Effect of the High Impact Exercise on Bone Density in Prepuberal Girls

Not Applicable

Suspended

• Conditions: Bone Loss, Age-Related,
• Interventions: Other: High Impact Exercise; Other: Low Impact Exercise

• Registration Number: NCT02488122
• Lead Sponsor: Fundación Santa Fe de Bogota

Brief Summary

Osteoporosis has become a worldwide concern an a matter of public health as osteoporosis is a major contributing factor associated with insufficiency fracture of the spine, wrist and proximal femur, and as a result, can diminish quality of life as well as increase direct and indirect healthcare costs.

The pathophysiology of osteoporosis is based on two main factors; low bone mass and age associated architectural changes within the bone, high impact exercise in childhood can improve the peak bone mass and bone architecture. The evidence suggests that bone adaptation to increased load is optimal in early puberty (Tanner stages I and II) since around 30% of total body adult bone mass is accrued during this period.

However, the optimal exercise program for increasing peak bone mineral content is still unclear. Therefore, the aim of this study is to assess if 15 minutes of high-impact exercise three times per week improve areal bone mineral density assessed by DXA of pre pubertal girls after a ten-month regimen compared to low-impact exercise. This information could highly impact the development of public health policies directed to pre pubertal girls.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-06-30
• Study First Submitted QC: 2015-07-01
• Study First Posted: 2015-07-02
• Status Verified: 2016-02
• Study Start: 2016-02
• Last Update Submitted: 2016-02-09
• Last Update Posted: 2016-02-11
• Primary Completion: 2016-11
• Study Completion: 2017-05

Recruitment & Eligibility

• Status: SUSPENDED
• Sex: Female
• Target Recruitment: 276

Inclusion Criteria

• Girls between ages 8 to 10
• Tanner I

Exclusion Criteria

• Precocious menarche (within the selected timeframe)
• Chronic disorders or medications known to affect bone metabolism or musculoskeletal function.
• Body Mass Index 30 or higher
• Regular vigorous physical activity (training more than 8 hours per week)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High Impact Exercise	High Impact Exercise	weight bearing exercises, jumps, plyometric exercises
Low Impact Exercise	Low Impact Exercise	Walking, Strength training, Cycling, Yoga.

Primary Outcome Measures

Name	Time	Method
bone mineral density (BMD) are presented for the total Body total bone mineral density	36 weeks	whole body whole Amount of mineral matter per square centimeter of bones.