To evaluate analgesic efficacy of various regional anaesthesia techniques in breast cancer surgery

Recruiting

• Registration Number: CTRI/2023/01/048917
• Lead Sponsor: HCG Hospital

Brief Summary

Patients undergoing breast surgery experience marked acute pain postoperatively. The axillary component of the surgery is responsible of the majority of this pain.When the postoperative pain is not controlled well, this leads to both psychological and physiological negative consequences. While effective control of the acute pain suppresses the surgical stress response and decreases the opioids and general anesthetics needs, that leads to preservation of the immune response. In addition, regional anesthesia can reduce the stress response caused by surgical trauma.Opioid based analgesic techniques are associated with hyperalgesia, tolerance and predisposition to chronic pain. Fascial plane blocks are emerging as novel analgesia techniques for breast surgery with favorable pain scores, improved patient satisfaction and quality of recovery with additional advantage of opioid sparing being reported in literature. The practice of taking up breast surgeries as day care procedures favor administrating analgesic techniques with minimal residual or adverse effects Interfascial blocks score over regional anesthetic techniques such as PVB as they have no risk of sympathetic blockade, intrathecal or epidural spread.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-02
• Last Update Posted: 2024-06-18

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

American Society of Aanaesthesiologist 1-3.

Exclusion Criteria

Non consenting Known allergy to study drugs Coagulation disorder Uncontrolled comorbidities Infection at surgical site.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative pain score with numeric rating scale at different post operative time periods beginning 0 hour till 48 hours after surgery	Immediate post operative period at 0 hour 2nd hour 6th hour 12th hour 24th hour and 48 hours after surgery

Secondary Outcome Measures

Name	Time	Method
Total postoperative opioid consumed	Time to first rescue analgesia (hr)

Trial Locations

Locations (1)

Health Care Global Enterprises Ltd; 🇮🇳 Bangalore, KARNATAKA, India

Health Care Global Enterprises Ltd

🇮🇳Bangalore, KARNATAKA, India

Sunil Kumar HR

Principal investigator

9241271214

drsunilkumar.r@hcgel.com